Guix-HPC is an effort to optimize GNU Guix for reproducible scientific workflows in high-performance computing (HPC). Our introductory article explains how we got started and gives an overview of what we want to achieve. We regularly publish articles on this Web site highlighting specific features or achievements. Stay tuned!

Guix-HPC is a joint software development project currently involving three research institutes: Inria, the Max Delbrück Center for Molecular Medicine (MDC), University of Tennessee Health Science Center (UTHSC) and the Utrecht Bioinformatics Center (UBC).

Talks & Papers

The material below covers our work and motivation for Guix-HPC:

Check out the Guix web site for more publications.


Most of the code developed for Guix-HPC aims to consolidate the code base and package collection of Guix proper, and thus be pushed upstream. This has already given rise to a large collection of bioinformatics, algebra, and R packages, as well as features to simplify Guix deployment on clusters.

Some auxiliary tools and package sets are maintained elsewhere, or kept in a staging area until they are mature enough to be submitted for inclusion in Guix:

  • The Guix Workflow Language, a lightweight framework implementing reproducible computational pipelines.
  • hpcguix-web is a web interface that allows users to search for packages and guides them the installation and the job submission process.
  • Check out the third-party channels providing scientific and HPC packages!

All this is free software that you are welcome to use and contribute to!

Cluster Deployments

Here are known deployments of Guix on clusters and contact information:

If you would like to be listed here, please email us at


There are several ways we can get in touch:

Join us!

If you are using Guix in an HPC context at your workplace, or if you would like to discuss ways to address your own HPC use cases, or if you are an HPC vendor interested in improving the software deployment experience for your users, please consider joining us!

  • MDC
  • Inria
  • UBC